She has denied using Botox to smooth her skin.

So viewers were at a loss to explain Jennifer Aniston’s oddly youthful complexion when she appeared on the Graham Norton Show.

The former Friends star, 45, looked strangely wrinkle free and expressionless when she sat down on the chat show host’s sofa on Friday night.

Viewer Katie bell said: ‘I love Jennifer Aniston a lot but why does her face look sooooo weird ‘.

Sarah Gray added: ‘Oh my god BIG let down jennifer Aniston has had Botox or a face lift’.

Sturat M added: ‘Did Jennifer Aniston really have to have that botox on her face? Surely would have looked better just her natural self.’

Miss Aniston has admitted using Botox ‘once’ in the past, but said she decided not to do it again. She told InStyle magazine in 2011: ‘It was not good. It makes women look older. Harder. The warmth in their faces goes away.

‘People think that I do a lot of injections, but I don’t. I’m not saying that I haven’t tried it… but I see how it’s a slippery slope. All that cosmetic stuff looks ridiculous on me.’

Instead, Miss Aniston says she swears by ‘laser peels’, which remove the outer layer of skin, reducing fine lines and supposedly boosting collagen.